FROM AWARD-WINNING AUTHOR DR GOVIND SHUKLA, NUTRITION EXPERT
Govind Shukla, Specializes in Pharmacology, Toxicology, Nutraceuticals & Herbal Drugs has published More than 100 research papers in National & International Journals. He is also a reviewer of International Journal of Pharmacology & pharmacotherapeutics, Chief editor of IJPNR Journal & Freelance Medical Writer for Different publication Groups including Lambert Academic Publishing Saarbrucken, Germany.
Disrupted sleep is associated with DNA Damage thus leads to life style disorders
Lack of proper sleep and night-time wakefulness can cause damage to the DNA structure and lead to many diseases, including cancer and diabetes, cardiovascular, neurological and pulmonary diseases, warns a study.
The study, published in the Anesthesia academic journal, shows that DNA repair gene expression is lower at baseline among night workers and further decreases after acute sleep deprivation, which supports the postulation that night workers demonstrate impaired DNA repair.
The findings showed that people who are required to work overnight demonstrate 30 per cent higher DNA breaks as compared with those not required to work overnight, and this DNA damage is further increased by over 25 per cent after a night of acute sleep deprivation.
For the study, the team examined a small group of healthy full-time doctors, average age between 28 and 33, who donated a sample of blood after three days of adequate sleep.Doctors who worked the night shift then had additional blood sampled the morning after, following acute sleep deprivation.
The study demonstrates that disrupted sleep is associated with DNA damage.
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